During the annual hot and rainy seasons across East Africa, West Africa, Southern Africa and tropical Central African pastoral regions, stagnant water wetlands, humid grasslands and soaring temperatures trigger frequent and explosive outbreaks of sheep black disease (infectious necrotic hepatitis). Sheep farmers in core African breeding countries including Kenya, Tanzania, South Africa, Nigeria and Ghana are facing a severe seasonal epidemic crisis: healthy grazing sheep suddenly develop persistent lethargy, mental depression and deep coma, and die acutely within 12 to 48 hours with almost no obvious pre-morbid symptoms. Most local African pastoralists lack professional veterinary identification capabilities, easily misjudging sheep black disease sudden death syndrome as heat stroke, enterotoxemia or blackleg, leading to delayed prevention and treatment, repeated epidemic outbreaks and massive irreversible flock economic losses.